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AbbVie Submits sNDA for Upadacitinib in Adults and Adolescents With Severe Alopecia Areata
AbbVie has submitted a supplemental new drug application (sNDA) to the FDA for upadacitinib (Rinvoq) to treat severe alopecia areata in adults and adolescents. This submission is based on phase 3 UP-AA trial data, which demonstrated significant scalp hair regrowth, including complete coverage in many patients. If approved, upadacitinib would be the second JAK inhibitor indicated for alopecia areata in the US, with trial results suggesting a new benchmark for efficacy.